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OpenNCT06526117View on ClinicalTrials.gov ↗ Report an issue with this listing

Stroke Prevention in Nigeria 2 Trial

Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II: A Multicenter, Open-label, Single-arm Type I Hybrid Clinical Trial

Race/ethnicity-specific condition

Phase

PHASE4

Enrollment

220 (est.)

Age range

5 Years to 12 Years

Sex

ALL

Summary

The primary goal of this study is to complete a multicenter single-arm, type I hybrid trial to assess the effectiveness of hydroxyurea therapy for primary stroke prevention in high-risk children with sickle cell anemia (SCA) living in Nigeria in routine care settings.

Conditions studied

Sickle Cell DiseaseStroke

Sponsors

Aminu Kano Teaching HospitalCollaborator
Murtala Muhammed Specialist HospitalCollaborator
National Institute of Neurological Disorders and Stroke (NINDS)Collaborator
Vanderbilt University Medical CenterLead

Study locations

Aminu Kano Teaching Hospital

Kano

Shehu U Abdullahi, MD, FWACPaed, CONTACT

Murtala Muhammad Specialist Hospital

Kano

Salma A Suwaid, MBBS FWACP, CONTACT